The University of Zagreb School of Medicine (UZSM/ZSM)is the oldest, most respected and largest institution offering medical studies in the Republic of Croatia. The decision on its establishment was adopted by the Croatian parliament in January 1917, which is a precedent in the Croatian higher education and testifies that already back then an awareness of the significance of academic medicine on the national ground existed, not only for the development of the medical profession, but also of the entire society. Classes officially started a year later after the inaugural lecture of Drago Perović About the direction of teaching and research in anatomy in the hall of the University of Zagreb. The first professors were appointed, which was followed by the establishment of the institutes: Department of Anatomy, Morphology‐Biological Institute, Medical‐Chemical Institute, Institute of Physiological, Pathological‐Anatomical Institute, Department of General Experimental Pathology and Pharmacology and Public Health Institute. In the period from 1920 to 1922 most of the clinical departments s were also established. In 1927, the Zagreb School of Medicine had a total of 17 teaching establishments, among which the oldest was the Sisters of Mercy Hospital, and in 1937 that number increased to 19. Most areas of the Faculty were on Šalata, on the area that was intended for the construction of the entire Medical School. In the academic year 1938/39, the total number of stu‐ dents at the Faculty was 921. After the Second World War, there was a need for more doctors, which in the year 1948/49 resulted in a significant increase in the number of students (2855). Since the academic year 1965/66, the practice of limited registration under the terms of an entry exam is established.